SS-31

SS-31 is presented here as a laboratory catalogue entry for research environments that need clear identification, labelled variants, and direct access to supporting records. The current listing includes 3 labelled variants: 10mg, 25mg, and 50mg. That structure keeps the page useful as both a procurement reference and an indexable resource covering stock visibility, pricing context, and documentation.

Within the wider Au Peptide Labs catalogue, SS-31 sits alongside Retatrutide, Tesamorelin, and Ipamorelin. Researchers often review neighbouring compounds before selecting a comparator or deciding which sequence belongs in a screening panel. Keeping those internal paths close to the product page improves traceability and helps laboratory buyers compare materials without relying on vague or consumer-style copy.

In research literature, SS-31 is generally treated as a tetrapeptide Szeto-Schiller compound (D-Arg-2′6′-dimethylTyr-Lys-Phe-NH₂) that selectively partitions to the inner mitochondrial membrane by binding cardiolipin. SS-31 (elamipretide) carries a net 3+ charge at physiological pH that drives electrophoretic accumulation at the negatively charged inner mitochondrial membrane (IMM). There it interacts with cardiolipin — an anionic phospholipid unique to the IMM and essential for cristae architecture and respiratory complex assembly. Cardiolipin-SS-31 binding has been studied for: stabilising cytochrome c interaction with Complex IV, improving electron transfer efficiency at Complex I and III, and reducing superoxide/H₂O₂ generation during oxidative stress conditions. The non-natural D-Arg and 2′6′-dimethylTyr residues confer protease resistance, enabling extended incubation in cell-based assay formats.

Research applications centre on mitochondrial bioenergetics and cardiolipin biology. SS-31 is frequently used as a positive control in mitochondrial ROS assays, cristae remodelling studies, and ATP synthesis efficiency experiments. Its protease-resistant design makes it suitable for primary cell cultures where longer peptide incubation times are needed. For laboratory teams, the practical emphasis is usually on sequence identity, receptor or pathway relevance where documented, and whether SS-31 behaves consistently across stability, purity, and analytical verification workflows. Variant labels on this page support clearer internal referencing when multiple labelled variants are under review.

If a product-specific file is not attached to this listing, the wider COA library remains the correct reference point for current published documentation. The COA section is useful for confirming how the product is labelled in the catalogue, whether purity information has been published, and whether the laboratory record for the material is complete before bench use.

When teams compare SS-31 with Retatrutide, Tesamorelin, and Ipamorelin, COA access also helps keep comparator decisions grounded in documented material identity rather than assumption. That is especially important for research pages that combine pricing, variant selection, and analytical records on a single URL.