Format
Sealed research vial
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99%+ Purity
Lab-grade supply. Limited AU stock.
A$199
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Certificate of Analysis
COA library
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PT-141
A$199
PT-141 is a melanocortin receptor analog studied in MC receptor subtype-selectivity and downstream signalling assays.
The five MCR subtypes show distinct tissue distributions and ligand preferences, making receptor-subtype selectivity a central question when designing assay panels. Comparing MT-I, MT-II, and PT-141 in parallel using subtype-selective antagonists (e.g., SHU-9119 at MC3/4R, AGRP at MC3/4R) allows attribution of cAMP responses to individual receptor populations.
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In research literature, PT-141 is generally treated as a melanocortin receptor analog studied in MC receptor subtype-selectivity and downstream signalling assays. The melanocortin receptor family comprises five subtypes (MC1R–MC5R), all class A GPCRs primarily coupling via Gs to adenylyl cyclase. Melanotan I (afamelanotide) is a 13-amino acid [Nle⁴,D-Phe⁷]-α-MSH analog with preferential MC1R selectivity in binding assays. Melanotan II is a cyclic α-MSH analog (Ac-Nle⁴-c[Asp⁵,D-Phe⁷,Lys¹⁰]-α-MSH) with broader selectivity across MC1R, MC3R, MC4R, and MC5R. PT-141 (bremelanotide) is a metabolite of MT-II lacking the N-terminal acetyl and C-terminal amide, which preserves MC3R and MC4R agonism relevant to CNS-focused neuroendocrine assay models while reducing some peripheral receptor activity versus its parent compound.
The five MCR subtypes show distinct tissue distributions and ligand preferences, making receptor-subtype selectivity a central question when designing assay panels. Comparing MT-I, MT-II, and PT-141 in parallel using subtype-selective antagonists (e.g., SHU-9119 at MC3/4R, AGRP at MC3/4R) allows attribution of cAMP responses to individual receptor populations. For laboratory teams, the practical emphasis is usually on sequence identity, receptor or pathway relevance where documented, and whether PT-141 behaves consistently across stability, purity, and analytical verification workflows. Variant labels on this page support clearer internal referencing when multiple labelled variants are under review.
Potential research applications for PT-141 should be framed strictly in analytical and laboratory terms. Typical reasons a team might review this product page include:
Handling decisions should always follow the vial label, internal SOPs, and any product-specific documentation. A conservative laboratory baseline for PT-141 is:
If a product-specific file is not attached to this listing, the wider COA library remains the correct reference point for current published documentation. The COA section is useful for confirming how the product is labelled in the catalogue, whether purity information has been published, and whether the laboratory record for the material is complete before bench use.
When teams compare PT-141 with Tesamorelin, NAD+, and Retatrutide, COA access also helps keep comparator decisions grounded in documented material identity rather than assumption. That is especially important for research pages that combine pricing, variant selection, and analytical records on a single URL.
Certificate of Analysis
COA library
Browse the current COA library and available product documentation.
It brings together 1 labelled variant: 10mg, current pricing context, stock visibility, COA access, and internal links to related catalogue pages so a laboratory buyer can review the material from a single reference URL.
PT-141 is generally discussed as a melanocortin receptor analog studied in MC receptor subtype-selectivity and downstream signalling assays. The most relevant background is sequence behaviour, pathway or receptor context where documented, and analytical consistency under controlled laboratory conditions.
Use the label, COA, and internal SOPs as the primary guide. In general, store the material under controlled laboratory conditions, minimise avoidable environmental exposure, and keep variant tracking records current.
This page links the broader COA library when a product-specific document is not attached. Laboratories should use the published documentation set that is currently available for the listing.
No. The page should be interpreted strictly in a research and laboratory context. It does not provide dosage guidance, treatment claims, or human or animal use instructions.
