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Third-party tested · 99%+ purity · Dispatched from Melbourne within 1 business day · 4.6★ on Trustpilot
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Certificate of Analysis
COA library
Browse the current COA library and available product documentation.
PT-141
COA-backed · third-party tested
Structural class
PT-141 is a melanocortin receptor analog studied in MC receptor subtype-selectivity and downstream signalling assays.
Pathways studied
The melanocortin receptor family comprises five subtypes (MC1R–MC5R), all class A GPCRs primarily coupling via Gs to adenylyl cyclase. Melanotan I (afamelanotide) is a 13-amino acid [Nle⁴,D-Phe⁷]-α-MSH analog with preferential MC1R selectivity in binding assays. Melanotan II is a cyclic α-MSH analog (Ac-Nle⁴-c[Asp⁵,D-Phe⁷,Lys¹⁰]-α-MSH) with broader selectivity across MC1R, MC3R, MC4R, and MC5R. PT-141 (bremelanotide) is a metabolite of MT-II lacking the N-terminal acetyl and C-terminal amide, which preserves MC3R and MC4R agonism relevant to CNS-focused neuroendocrine assay models while reducing some peripheral receptor activity versus its parent compound.
Typical research focus
The five MCR subtypes show distinct tissue distributions and ligand preferences, making receptor-subtype selectivity a central question when designing assay panels. Comparing MT-I, MT-II, and PT-141 in parallel using subtype-selective antagonists (e.g., SHU-9119 at MC3/4R, AGRP at MC3/4R) allows attribution of cAMP responses to individual receptor populations.
For laboratory research use only. Not for human or veterinary use, and not for human consumption. Intended for in-vitro and pre-clinical research settings only.
How to read a certificate of analysis, what purity actually measures, and how research peptides are stored and independently verified.
The questions researchers ask most.
Every batch is independently tested by Janoshik Analytical. Each product links straight to the lab's own record, so you can check the exact purity figure yourself before you buy — nothing to take on trust.
Keep vials sealed, dry, and out of direct light. Lyophilised (freeze-dried) peptides are stable at -20 °C; once reconstituted, store as noted on the product label. Full handling notes sit on every product page.
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More in the full FAQ · Rated 4.6★ on Trustpilot
Researchers who bought PT-141 also stock these.
It brings together 1 labelled variant: 10mg, current pricing context, stock visibility, COA access, and internal links to related catalogue pages so a laboratory buyer can review the material from a single reference URL.
PT-141 is generally discussed as a melanocortin receptor analog studied in MC receptor subtype-selectivity and downstream signalling assays. The most relevant background is sequence behaviour, pathway or receptor context where documented, and analytical consistency under controlled laboratory conditions.
Use the label, COA, and internal SOPs as the primary guide. In general, store the material under controlled laboratory conditions, minimise avoidable environmental exposure, and keep variant tracking records current.
This page links the broader COA library when a product-specific document is not attached. Laboratories should use the published documentation set that is currently available for the listing.
No. The page should be interpreted strictly in a research and laboratory context. It does not provide dosage guidance, treatment claims, or human or animal use instructions.
