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Every batch is independently tested by Janoshik Analytical. Each product links straight to the lab's own record, so you can check the exact purity figure yourself before you buy — nothing to take on trust.

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Sealed research vial
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Certificate of Analysis
Certificate of Analysis
Verified purity: 99.490%
GHK-CU
99.49% purity · COA verified
Structural class
GHK-CU is a copper(II)-binding tripeptide (Gly-His-Lys) that forms a stable 1:1 complex with Cu²⁺ and is studied in extracellular matrix gene-expression and wound-signalling assay models.
Pathways studied
GHK binds Cu²⁺ with extraordinary affinity (Kd ≈ 10⁻¹⁵ M) via coordination through the glycine α-amino group, histidine imidazole Nδ, and the lysine α-amino group — a square-planar complex that remains intact under physiological conditions. The copper-loaded form (GHK-Cu) has been studied for upregulation of collagen I, collagen III, fibronectin, and the proteoglycan decorin in fibroblast assay models, with mechanistic proposals centring on TGF-β pathway modulation and activation of metalloenzymes. Gene-expression profiling studies report broad transcriptional changes across matrix-remodelling, antioxidant defence, and neurotrophin-related gene sets, making it a tool for wide-scope transcriptomic research in addition to targeted pathway assays.
Typical research focus
The copper complex changes the optical and electrochemical properties of the peptide relative to the metal-free form, which makes analytical characterisation methods (UV-Vis, circular dichroism, ICP-MS for copper quantification) relevant workflow steps before cell-based experiments. Comparative studies between GHK and GHK-Cu allow researchers to attribute transcriptional or matrix effects specifically to copper coordination versus the bare tripeptide scaffold.
For laboratory research use only. Not for human or veterinary use, and not for human consumption. Intended for in-vitro and pre-clinical research settings only.
How to read a certificate of analysis, what purity actually measures, and how research peptides are stored and independently verified.
The questions researchers ask most.
Every batch is independently tested by Janoshik Analytical. Each product links straight to the lab's own record, so you can check the exact purity figure yourself before you buy — nothing to take on trust.
Keep vials sealed, dry, and out of direct light. Lyophilised (freeze-dried) peptides are stable at -20 °C; once reconstituted, store as noted on the product label. Full handling notes sit on every product page.
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Researchers who bought GHK-CU also stock these.
It brings together 2 labelled variants: 50mg and 100mg, current pricing context, stock visibility, COA access, and internal links to related catalogue pages so a laboratory buyer can review the material from a single reference URL.
GHK-CU is generally discussed as a copper(II)-binding tripeptide (Gly-His-Lys) that forms a stable 1:1 complex with Cu²⁺ and is studied in extracellular matrix gene-expression and wound-signalling assay models. The most relevant background is sequence behaviour, pathway or receptor context where documented, and analytical consistency under controlled laboratory conditions.
Use the label, COA, and internal SOPs as the primary guide. In general, store the material under controlled laboratory conditions, minimise avoidable environmental exposure, and keep variant tracking records current.
Yes. This listing includes access to a product-specific COA, which should be reviewed before use so purity, identity, and documentation checks are aligned with the project record.
No. The page should be interpreted strictly in a research and laboratory context. It does not provide dosage guidance, treatment claims, or human or animal use instructions.