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99%+ PurityLab-grade stock
5-Amino product image

Format

Sealed research vial

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COA-backed inventory

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99%+ Purity

5-Amino

Lab-grade supply. Limited AU stock.

A$269

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Certificate of Analysis

COA library

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Overview

5-Amino is presented here as a laboratory catalogue entry for research environments that need clear identification, labelled variants, and direct access to supporting records. The current listing includes 1 labelled variant: 50mg. That structure keeps the page useful as both a procurement reference and an indexable resource covering stock visibility, pricing context, and documentation.

Within the wider Au Peptide Labs catalogue, 5-Amino sits alongside Retatrutide, Tesamorelin, and Ipamorelin. Researchers often review neighbouring compounds before selecting a comparator or deciding which sequence belongs in a screening panel. Keeping those internal paths close to the product page improves traceability and helps laboratory buyers compare materials without relying on vague or consumer-style copy.

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Research Background

In research literature, 5-Amino is generally treated as 5-amino-1-methylquinolinium (5-amino-1MQ), a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in one-carbon metabolism and epigenetic methylation research. 5-amino-1MQ competitively inhibits NNMT — an enzyme that converts nicotinamide (vitamin B3) to 1-methylnicotinamide using S-adenosylmethionine (SAM) as the methyl donor. By blocking this reaction, 5-amino-1MQ increases the cellular SAM:SAH (S-adenosylhomocysteine) ratio, which enhances the methyl-donor capacity of the one-carbon pool available to histone and DNA methyltransferases. This shifts the epigenetic landscape toward increased H3K4me3 and H3K27me3 marks in cell models, linking NNMT inhibition to chromatin remodelling research. NNMT is overexpressed in multiple adipose tissue depots and certain cancer types, making it a target of interest in both metabolic and oncology research contexts.

Unlike the peptides in this catalogue, 5-amino-1MQ is a quinolinium small molecule — its research applications centre on enzyme inhibition biochemistry, one-carbon cycle flux analysis, and epigenomic profiling rather than receptor pharmacology. Isotope tracing experiments (¹³C-methionine or ²H-SAM) are frequently used alongside NNMT inhibitors to map methyl group flux quantitatively. For laboratory teams, the practical emphasis is usually on sequence identity, receptor or pathway relevance where documented, and whether 5-Amino behaves consistently across stability, purity, and analytical verification workflows. Variant labels on this page support clearer internal referencing when multiple labelled variants are under review.

Potential Research Applications

Potential research applications for 5-Amino should be framed strictly in analytical and laboratory terms. Typical reasons a team might review this product page include:

  • NNMT enzyme inhibition assays measuring 1-methylnicotinamide production by HPLC or fluorescence-based readouts with 5-amino-1MQ as the test compound.
  • SAM:SAH ratio quantification by LC-MS/MS in cell models to confirm one-carbon cycle flux changes upon NNMT inhibition.
  • Histone methylation ChIP-seq or ChIP-qPCR studies examining H3K4me3/H3K27me3 changes downstream of 5-amino-1MQ treatment.
  • NNMT overexpression / knockdown comparator panels using 5-amino-1MQ as the pharmacological control alongside siRNA knockdown conditions.

Laboratory Handling & Storage

Handling decisions should always follow the vial label, internal SOPs, and any product-specific documentation. A conservative laboratory baseline for 5-Amino is:

  • Store at room temperature or –20 °C in a desiccated environment; quinolinium compounds can be hygroscopic.
  • Dissolve in DMSO to prepare a concentrated stock (typically 10–50 mM); dilute into aqueous buffers immediately before use to prevent precipitation.
  • Use vehicle (DMSO) controls at matched concentration in all cell-based assays — DMSO at >0.1% affects cellular methylation status independently.
  • Confirm purity by HPLC and identity by mass spectrometry (MW ≈ 174 Da) against COA before enzyme or cell-based experiments.

Certificate of Analysis (COA)

If a product-specific file is not attached to this listing, the wider COA library remains the correct reference point for current published documentation. The COA section is useful for confirming how the product is labelled in the catalogue, whether purity information has been published, and whether the laboratory record for the material is complete before bench use.

When teams compare 5-Amino with Retatrutide, Tesamorelin, and Ipamorelin, COA access also helps keep comparator decisions grounded in documented material identity rather than assumption. That is especially important for research pages that combine pricing, variant selection, and analytical records on a single URL.

Certificate of Analysis

COA library

Browse the current COA library and available product documentation.

View COA library

Frequently Asked Questions

What does this 5-Amino page cover?

It brings together 1 labelled variant: 50mg, current pricing context, stock visibility, COA access, and internal links to related catalogue pages so a laboratory buyer can review the material from a single reference URL.

How is 5-Amino usually positioned in research discussions?

5-Amino is generally discussed as 5-amino-1-methylquinolinium (5-amino-1MQ), a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in one-carbon metabolism and epigenetic methylation research. The most relevant background is sequence behaviour, pathway or receptor context where documented, and analytical consistency under controlled laboratory conditions.

How should 5-Amino be handled after receipt?

Use the label, COA, and internal SOPs as the primary guide. In general, store the material under controlled laboratory conditions, minimise avoidable environmental exposure, and keep variant tracking records current.

Is 5-Amino accompanied by a certificate of analysis?

This page links the broader COA library when a product-specific document is not attached. Laboratories should use the published documentation set that is currently available for the listing.

Is 5-Amino sold for human or veterinary use?

No. The page should be interpreted strictly in a research and laboratory context. It does not provide dosage guidance, treatment claims, or human or animal use instructions.

Research Resources

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