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Certificate of Analysis
COA library
Browse the current COA library and available product documentation.
Structural class
5-Amino is 5-amino-1-methylquinolinium (5-amino-1MQ), a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in one-carbon metabolism and epigenetic methylation research.
Pathways studied
5-amino-1MQ competitively inhibits NNMT — an enzyme that converts nicotinamide (vitamin B3) to 1-methylnicotinamide using S-adenosylmethionine (SAM) as the methyl donor. By blocking this reaction, 5-amino-1MQ increases the cellular SAM:SAH (S-adenosylhomocysteine) ratio, which enhances the methyl-donor capacity of the one-carbon pool available to histone and DNA methyltransferases. This shifts the epigenetic landscape toward increased H3K4me3 and H3K27me3 marks in cell models, linking NNMT inhibition to chromatin remodelling research. NNMT is overexpressed in multiple adipose tissue depots and certain cancer types, making it a target of interest in both metabolic and oncology research contexts.
Typical research focus
Unlike the peptides in this catalogue, 5-amino-1MQ is a quinolinium small molecule — its research applications centre on enzyme inhibition biochemistry, one-carbon cycle flux analysis, and epigenomic profiling rather than receptor pharmacology. Isotope tracing experiments (¹³C-methionine or ²H-SAM) are frequently used alongside NNMT inhibitors to map methyl group flux quantitatively.
For laboratory research use only. Not for human or veterinary use, and not for human consumption. Intended for in-vitro and pre-clinical research settings only.
How to read a certificate of analysis, what purity actually measures, and how research peptides are stored and independently verified.
The questions researchers ask most.
Every batch is independently tested by Janoshik Analytical. Each product links straight to the lab's own record, so you can check the exact purity figure yourself before you buy — nothing to take on trust.
Keep vials sealed, dry, and out of direct light. Lyophilised (freeze-dried) peptides are stable at -20 °C; once reconstituted, store as noted on the product label. Full handling notes sit on every product page.
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More in the full FAQ · Rated 4.6★ on Trustpilot
Researchers who bought 5-Amino also stock these.
It brings together 1 labelled variant: 50mg, current pricing context, stock visibility, COA access, and internal links to related catalogue pages so a laboratory buyer can review the material from a single reference URL.
5-Amino is generally discussed as 5-amino-1-methylquinolinium (5-amino-1MQ), a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in one-carbon metabolism and epigenetic methylation research. The most relevant background is sequence behaviour, pathway or receptor context where documented, and analytical consistency under controlled laboratory conditions.
Use the label, COA, and internal SOPs as the primary guide. In general, store the material under controlled laboratory conditions, minimise avoidable environmental exposure, and keep variant tracking records current.
This page links the broader COA library when a product-specific document is not attached. Laboratories should use the published documentation set that is currently available for the listing.
No. The page should be interpreted strictly in a research and laboratory context. It does not provide dosage guidance, treatment claims, or human or animal use instructions.
