Format
Sealed research vial
Trust signal
COA-backed inventory
Metabolic & GLP-1 · Research grade
Lab-grade supply. Stocked in Australia.
A$229
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Fast AU dispatch, tracked delivery, and documentation-ready inventory.
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High purity, consistent supply, and fast AU-wide dispatch.
Certificate of Analysis
COA library
Browse the current COA library and available product documentation.
Structural class
P176-191 (HGH-frag) is a growth-hormone-axis research peptide.
Pathways studied
Peptides in the GH-axis research class act primarily at two receptor targets: the growth-hormone-releasing hormone receptor (GHRHR), a class B GPCR that couples Gs to cAMP/PKA and GH gene transcription in somatotroph cell models; or the ghrelin/GH secretagogue receptor (GHSR-1a), a constitutively active class A GPCR whose agonism also triggers Gq-IP3 calcium flux in addition to Gs signalling. GHRH analogs (sermorelin, tesamorelin, CJC-1295) target GHRHR; ghrelin mimetics (GHRP-2, GHRP-6, ipamorelin) target GHSR-1a. CJC-1295 with DAC uses a reactive maleimide group to form a covalent thioether bond with albumin Cys34, extending half-life to days — an unusual mechanism studied in covalent protein-binding and pharmacokinetic assays. Ipamorelin is notable for GHSR-1a selectivity with minimal off-target ACTH or cortisol pathway stimulation in pituitary cell assays, distinguishing it from less selective GHRP-6.
Typical research focus
Research panels in this class typically compare GHRHR versus GHSR-1a pathway contributions, examine how DAC versus non-DAC half-life extension changes receptor-occupancy kinetics, or profile selectivity differences between ipamorelin and non-selective secretagogues. The GH fragment AOD-9604 (residues 176–191 of the GH sequence) is separately relevant as a lipolytic fragment that activates β3-adrenergic receptor signalling in adipocyte assays without engaging the somatotropic axis or IGF-1R.
For laboratory research use only. Not for human or veterinary use, and not for human consumption. Intended for in-vitro and pre-clinical research settings only.
How to read a certificate of analysis, what purity actually measures, and how research peptides are stored and independently verified.
The questions researchers ask most.
Every batch is independently tested by Janoshik Analytical. Each product links straight to the lab's own record, so you can check the exact purity figure yourself before you buy — nothing to take on trust.
Keep vials sealed, dry, and out of direct light. Lyophilised (freeze-dried) peptides are stable at -20 °C; once reconstituted, store as noted on the product label. Full handling notes sit on every product page.
Order by 2pm for same-day dispatch from our Melbourne warehouse, otherwise the next business day, with tracked delivery Australia-wide. No customs, no border delays — it's already in the country.
More in the full FAQ · Rated 4.6★ on Trustpilot
Researchers who bought P176-191 (HGH-frag) also stock these.
It brings together 2 labelled variants: 5mg and 10mg, current pricing context, stock visibility, COA access, and internal links to related catalogue pages so a laboratory buyer can review the material from a single reference URL.
P176-191 (HGH-frag) is generally discussed as a growth-hormone-axis research peptide. The most relevant background is sequence behaviour, pathway or receptor context where documented, and analytical consistency under controlled laboratory conditions.
Use the label, COA, and internal SOPs as the primary guide. In general, store the material under controlled laboratory conditions, minimise avoidable environmental exposure, and keep variant tracking records current.
This page links the broader COA library when a product-specific document is not attached. Laboratories should use the published documentation set that is currently available for the listing.
No. The page should be interpreted strictly in a research and laboratory context. It does not provide dosage guidance, treatment claims, or human or animal use instructions.
